کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3442706 | 1595029 | 2006 | 6 صفحه PDF | دانلود رایگان |
ObjectiveThe purpose of this study was to determine the effects of 3 intravaginal antibacterial treatments on vaginal lactobacilli in patients with bacterial vaginosis (BV).Study designRetrospective analyses were performed on Lactobacillus scores from 3 similar studies evaluating 2 2% clindamycin vaginal creams and 0.75% metronidazole gel at baseline and at 21 to 30 days in 408 patients with BV. Scores were compared using a 1-way global F test and McNemar's test.ResultsAll groups had similar mean Lactobacillus scores at baseline (P = 0.37) and at 21 to 30 days (P = .71). The 3 groups were also comparable at both visits with respect to the distributions of scores within each group. In all groups, there was significant improvement in the percentages of patients with no lactobacilli present at 21 to 30 days compared with baseline (P < .0001 for all comparisons).ConclusionClindamycin and metronidazole promoted similar levels of restoration of vaginal lactobacilli at 21 to 30 days.
Journal: American Journal of Obstetrics and Gynecology - Volume 194, Issue 5, May 2006, Pages 1277–1282