کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3443780 1595238 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A prospective analysis of diet quality and endometrial cancer among 84,415 postmenopausal women in the Women's Health Initiative
ترجمه فارسی عنوان
تجزیه و تحلیل آینده نگر از کیفیت رژیم غذایی و سرطان آندومتر در بین 84415 زن یائسه در ابتکار بهداشت زنان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

PurposeEndometrial cancer is the most commonly diagnosed gynecologic cancer, but no convincing dietary risk factors for this cancer have been identified. Among postmenopausal women, we examined how four key a priori diet quality indices—the Healthy Eating Index-2010, Alternative Healthy Eating Index-2010, alternate Mediterranean Diet, and Dietary Approaches to Stop Hypertension are related to the risk of endometrial cancer in the Women's Health Initiative Clinical Trials and Observational Study.MethodsOur prospective cohort study included 84,415 postmenopausal women with a uterus who completed a food frequency questionnaire at enrollment. Cox proportional hazards models were used to estimate multivariate hazard ratios (HRs) and 95% confidence intervals (CIs) for endometrial cancer associated with increasing quintiles of diet quality index scores.ResultsDuring 13.3 years of follow-up, 1392 endometrial cancer cases occurred. After adjustment for known risk factors, having better diet quality (Q5 vs. Q1) was not associated with the risk of endometrial cancer, as evidenced using Healthy Eating Index-2010 (HR: 1.11, 95% CI: 0.93–1.33), Alternative Healthy Eating Index-2010 (HR: 0.98, 95% CI: 0.82–1.17), alternate Mediterranean Diet (HR: 0.98, 95% CI: 0.82–1.17), or Dietary Approaches to Stop Hypertension (HR: 1.00, 95% CI: 0.84–1.19).ConclusionsDiet quality was not associated with endometrial cancer risk in this large cohort of postmenopausal women.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Annals of Epidemiology - Volume 25, Issue 10, October 2015, Pages 788–793
نویسندگان
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