Timed Up and Go, Cognitive, and Quality-of-Life Correlates in Parkinson's Disease

ObjectiveTo examine the relationship between Timed Up and Go (TUG) performance, verbal executive function (EF) performance, and quality-of-life (QOL) measures in Parkinson's disease (PD).DesignCross-sectional.SettingSixteen movement disorder centers from across the United States.ParticipantsPatients with PD (N=1964).InterventionsNot applicable.Main Outcome MeasuresTUG test, immediate and delayed 5-word recall, verbal fluency, PD QOL Questionnaire.ResultsTUG performance and verbal EF performance were significantly associated with, and predictors of, QOL measures, having the greatest association and predictability with the mobility domain of the QOL measures.ConclusionsThe TUG test and verbal EF tests have QOL correlates, making the combined evaluation of mobility, cognitive, and QOL decline a potential examination tool to evaluate the sequelae of PD.