Results of an Active Neurodynamic Mobilization Program in Patients With Fibromyalgia Syndrome: A Randomized Controlled Trial

ObjectiveTo examine the effects of an active neurodynamic mobilization program on pain, neurodynamics, perceived health state, and fatigue in patients with fibromyalgia syndrome (FMS).DesignRandomized controlled trial.SettingLocal fibromyalgia association.ParticipantsPatients with FMS (N=48).InterventionsPatients were randomly allocated to an active neurodynamic mobilization program or a control group. The intervention was performed twice a week.Main Outcome MeasuresPain was assessed with the Brief Pain Inventory and Pain Catastrophizing Scale; neurodynamics were evaluated using neurodynamic tests for upper and lower limbs. The functional state was evaluated with the Health Assessment Questionnaire Disability Index, and perceived fatigue was evaluated with the Fatigue Severity Scale.ResultsSignificant (P<.05) between-groups differences were found in the values of pain, upper and lower limb neurodynamics, functional state, and fatigue. Also, significant pre- to postintervention within-group differences were found in the intervention group, whereas no significant changes were found in the control group.ConclusionsA neurodynamic mobilization program is effective in improving pain, neurodynamics, functional status, and fatigue in patients with FMS.