کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3450327 1595738 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Freezing of Gait and Activity Limitations in People With Parkinson's Disease
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Freezing of Gait and Activity Limitations in People With Parkinson's Disease
چکیده انگلیسی

Tan DM, McGinley JL, Danoudis ME, Iansek R, Morris ME. Freezing of gait and activity limitations in people with Parkinson's disease.ObjectivesTo investigate the relationships between freezing of gait (FOG) and activity limitations in ambulant people with Parkinson's disease (PD), and to explore the contribution of FOG and gait hypokinesia to activity limitations after adjusting for the effects of disease severity.DesignRetrospective, cross-sectional design.SettingParticipants were recruited from neurologists' clinics and the general public in metropolitan Melbourne, Australia.ParticipantsVolunteers were screened for eligibility using the following inclusion criteria: diagnosis of idiopathic PD, modified Hoehn and Yahr stages 0 to IV, without dementia. Participants (N=210) were tested (mean age ± SD, 67.9±9.6y; mean PD duration ± SD, 6.7±5.6y; median Hoehn and Yahr stage=2.5).InterventionsNot applicable.Main Outcome MeasuresFOG was measured using the FOG questionnaire. Gait hypokinesia was quantified using both the 6-meter walk test and the Timed Up and Go test. Activity limitation was measured using the modified Unified Parkinson's Disease Rating Scale activities of daily living (ADL) section and the Schwab and England ADL scale.ResultsSeverity of gait freezing correlated significantly with the level of activity limitation (Spearman correlation coefficient, ρ=−.49 to .48; P<.001). A hierarchic regression model showed that disease severity explained 37.5% of the variance in Schwab and England ADL score (P<.001). Gait hypokinesia and FOG severity scores explained an additional 9.1% of the variance in activity limitation (R2 change=.091; P<.001).ConclusionsFOG severity and gait hypokinesia were associated with reduced levels of activity after adjusting for disease severity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Physical Medicine and Rehabilitation - Volume 92, Issue 7, July 2011, Pages 1159–1165
نویسندگان
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