Cost-Effectiveness of C-Leg Compared With Non–Microprocessor-Controlled Knees: A Modeling Approach

Brodtkorb T-H, Henriksson M, Johannesen-Munk K, Thidell F. Cost-effectiveness of C-Leg compared with non–microprocessor-controlled knees: a modeling approach.ObjectiveTo estimate the costs and health outcomes of C-Leg and non–microprocessor-controlled (NMC) knees using a decision-analytic model.DesignData on costs, rates and duration of problems, knee survival, and health-related quality of life were obtained from interviews with patients and prosthetists with experience of both C-Leg and NMC knees. Interview data were assessed in a decision-analytic Markov model to estimate cost-effectiveness from a health care perspective.SettingOutpatient.ParticipantsA population sample of 20 patients currently using the C-Leg and prior experience of nonmicroprocessor knees, and 5 prosthetists.InterventionsNot applicable.Main Outcome MeasureIncremental cost per quality-adjusted life year (QALY).ResultsThe mean incremental cost (in 2006 Euros) and QALYs for the C-Leg was €7657 and 2.38, respectively, yielding a cost per QALY gained of €3218.ConclusionsIt is important to provide decision-makers with relevant information on costs and health outcomes of different treatment strategies on actual decision problems despite limited evidence. The results of the study, taking into account both costs and a broadly defined health outcome in terms of QALY, show that given existing albeit limited evidence the C-Leg appears to yield positive health outcomes at an acceptable cost.