کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3454402 1595966 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evaluation of hepatoprotective activity of alcoholic and aqueous extracts of Selaginella lepidophylla
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Evaluation of hepatoprotective activity of alcoholic and aqueous extracts of Selaginella lepidophylla
چکیده انگلیسی

ObjectiveTo screen Selaginella lepidophylla (S. lepidophylla) that are used in traditional medicine for their claimed hepatoprotective properties.MethodsAlcoholic and aqueous extracts of S. lepidophylla were evaluated for their hepatoprotective activity using CCl4 and paracetamol induced acute hepatic injury model.ResultsTreatment with CCl4 and paracetamol significantly increased liver weight and volume compared to the normal group. Pretreatment with silymarin alcoholic and aqueous extracts significantly prevent increase in liver weight and volume.ConclusionsFrom the present experimental study it can be concluded that alcoholic and aqueous extract of S. lepidophylla exhibited significant hepatoprotective activity against CCl4 and paracetamol induced hepatotoxicity in rats, as result showed in physical, biochemical and histopathological parameters.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Asian Pacific Journal of Tropical Disease - Volume 4, Supplement 1, 2014, Pages S81-S86