کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3454466 1595966 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Prognostic implications of ischemia modified albumin in known cases of 86 elderly hypertensive South Asian aged 56–64 years – a hospital based study
ترجمه فارسی عنوان
پیامدهای پیش آگهی آلبومین اصلاح شده ایسکمی در موارد شناخته شده 86 سالمند مبتلا به فشار خون بالا در جنوب آسیا 56 ساله 64 ساله ؟؟ یک مطالعه در بیمارستان
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

ObjectiveTo study associated ischemia modified albumin in hypertensive participants and to compare the results with normotensive healthy controls.MethodsA total of 86 hypertensive patients and 86 age-sex matched normotensive healthy volunteers were selected for this study. The study was conducted for a period of 3 years from September 2007 to August 2010. Biochemical parameters and other parameters such as smoking habits, systolic and diastolic blood pressure and family history were recorded. Lipid profile, ischemia modified albumin, malondialdehyde and conjugated diene were measured by standard methods and results were compared between patients and controls.ResultsTotal cholesterol, triglycerides, low density lipoprotein cholesterol were significantly higher (P<0.001) in hypertensive subjects when compared to normotensive control. Also, significant differences were seen in high density lipoprotein cholesterol levels between both groups (P<0.001). The index of lipid per oxidation comprising both malondialdehyde and conjugated dienes were significantly higher in hypertensive compared to normotensive controls. Ischemia modified albumin levels were significantly increased among hypertensive compared to normotensive controls (P<0.001).ConclusionsHypertensive patients have increased oxidative stress and are accompanied with rise in ischemia modified albumin. Ischemia modified albumin could be incorporated as a diagnostic test parameter in hypertensive to avoid the future acute coronary complications.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Asian Pacific Journal of Tropical Disease - Volume 4, Supplement 1, 2014, Pages S429-S434