Antidiarrhoeal efficacy of Mangifera indica seed kernel on Swiss albino mice

ObjectiveTo examine the antidiarrhoeal activity of alcoholic and aqueous seed kernel extract of Mangifera indica (M. indica) on castor oil-induced diarrhoeal activity in Swiss albino mice.MethodsMango seed kernels were processed and extracted using alcohol and water. Antidiarrhoeal activity of the extracts were assessed using intestinal motility and faecal score methods.ResultsAqueous and alcoholic extracts of M. indica significantly reduced intestinal motility and faecal score in Swiss albino mice.ConclusionsThe present study shows the traditional claim on the use of M. indica seed kernel for treating diarrhoea in Southern parts of India.