کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3462853 1231519 2012 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nonparametric estimation of age-specific reference percentile curves with radial smoothing
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Nonparametric estimation of age-specific reference percentile curves with radial smoothing
چکیده انگلیسی

Reference percentile curves represent the covariate-dependent distribution of a quantitative measurement and are often used to summarize and monitor dynamic processes such as human growth. We propose a new nonparametric method based on a radial smoothing (RS) technique to estimate age-specific reference percentile curves assuming the underlying distribution is relatively close to normal. We compared the RS method with both the LMS and the generalized additive models for location, scale and shape (GAMLSS) methods using simulated data and found that our method has smaller estimation error than the two existing methods. We also applied the new method to analyze height growth data from children being followed in a clinical observational study of growth hormone treatment, and compared the growth curves between those with growth disorders and the general population.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Contemporary Clinical Trials - Volume 33, Issue 1, January 2012, Pages 13–22
نویسندگان
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