کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3463246 | 1231542 | 2008 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Analysis of a crossover clinical trial by permutation methods
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
An initially balanced crossover design is analyzed by permutation rather than parametric methods in order to obtain exact distribution-free significance levels, thus controlling type I error and increasing power. The analysis is first restricted to those subjects who completed all nine periods. Next, it is extended to those who successfully completed two of the three blocks of treatments or six periods. Finally, we show how these distribution-free results may be extended to any number of treatment sequences and treatments in a balanced crossover design.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Contemporary Clinical Trials - Volume 29, Issue 4, July 2008, Pages 565–568
Journal: Contemporary Clinical Trials - Volume 29, Issue 4, July 2008, Pages 565–568
نویسندگان
Phillip Good, Fang Xie,