کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3476627 1233271 2012 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Change in brain perfusion after extracranial–intracranial bypass surgery detected using the mean transit time of computed tomography perfusion
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Change in brain perfusion after extracranial–intracranial bypass surgery detected using the mean transit time of computed tomography perfusion
چکیده انگلیسی

BackgroundCerebral perfusion can be evaluated using a computed tomography (CT) scan by intravenous bolus injection of contrast media. The purpose of this study was to investigate the value of CT perfusion (CTP) in follow-up of extracranial–intracranial (EC-IC) bypass surgery.MethodsWe retrospectively reviewed pre- and postoperative CTP studies in 14 patients who received EC-IC bypass surgery because of cerebral arterial occlusion or stenosis. Brain areas showing prolongation of the mean transit time (MTT) were automatically identified and quantitatively measured.ResultsAll 14 patients showed MTT prolongation in the preoperative CTP study. In 13 patients, a reduction in brain volume with MTT prolongation was noted during postoperative CTP. These 13 patients had a patent EC-IC anastomosis, and 42 ± 21% of the brain area with MTT prolongation returned to normal MTT during CTP 7 ± 4 days (range 2–13 days) after surgery. On clinical follow up of 41 ± 16 months (range 14–60 months), no stroke or transient ischemic attack was noted after bypass surgery in these 13 patients. The brain volume with MTT prolongation did not decrease in just one patient whose EC-IC anastomosis was not patent, and the patient suffered a minor stroke during surgery.ConclusionQuantitative results for the brain area with MTT prolongation were positively correlated with improvement in brain perfusion shown on MTT, EC-IC bypass patency, and patient outcome.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Chinese Medical Association - Volume 75, Issue 12, December 2012, Pages 649–653
نویسندگان
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