کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3479350 | 1233447 | 2012 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Dextromethorphan in the treatment of early myoclonic encephalopathy evolving into migrating partial seizures in infancy Dextromethorphan in the treatment of early myoclonic encephalopathy evolving into migrating partial seizures in infancy](/preview/png/3479350.png)
Epileptic encephalopathy with suppression-burst in electroencephalography (EEG) can evolve into a few types of epileptic syndromes. We present here an unusual case of early myoclonic encephalopathy that evolved into migrating partial seizures in infancy. A female neonate initially had erratic myoclonus movements, hiccups, and a suppression-burst pattern in EEG that was compatible with early myoclonic encephalopathy. The seizures were controlled with dextromethorphan (20 mg/kg), and a suppression-burst pattern in EEG was reverted to relatively normal background activity. However, at 72 days of age, alternating focal tonic seizures, compatible with migrating partial seizures in infancy, were demonstrated by the 24-hour EEG recording. The seizures responded poorly to dextromethorphan. To our knowledge, this is the first reported case of early myoclonic encephalopathy evolving into migrating partial seizure in infancy. Whether it represents another age-dependent epilepsy evolution needs more clinical observation.
Journal: Journal of the Formosan Medical Association - Volume 111, Issue 5, May 2012, Pages 290–294