Diffuse large B-cell lymphoma of cerebellum five months after left atrial myxoma resection in an old woman

We describe a 70-year-old female patient with diffuse large B-cell lymphoma of the cerebellum; she received resection of a left atrial myxoma five months ago. To the best of our knowledge, to date no association of atrial myxoma with the malignant cerebellar diffuse large B-cell lymphoma has been reported in the literature, except for high level of interleukin-6 (IL-6) in the serum under both conditions. IL-6 as a pro-inflammatory cytokine has been shown to be associated with tumor progression, including inhibition of cancer cell apoptosis and stimulation of angiogenesis. IL-6 concentrations may provide possible aetiological links between atrial myxoma and cerebellar diffuse large B-cell lymphoma in our case.