Serum resistin and adiponectin concentrations in patients with overweight and obesity

ObjectiveTo explore the serum levels of resistin and adiponectin in patients with overweight and obesity.MethodsFifty-eight cases with normal weight and 24 patients with overweight and obesity have taken fasting blood samples for measurements of plasma glucose, plasma lipids, insulin, C-peptide, thyroid hormones, C-response protein, interleukin-6, TNF-α, leptin, adiponectin and resistin.ResultsThe concentrations of resistin in cases with overweight and obesity were significant higher than those in the normal weight cases (16.01 ± 8.60 vs 11.63 ± 9.05 ng/ml, P = 0.047). Pearson relation analysis showed that serum resistin concentrations were positively correlated with age (r = 0.476, P = 0.019), but negatively correlated with C-peptide (r = −0.45, P = 0.024), and adiponectin concentrations were positively correlated with HDL-c (r = 0.463, P = 0.023) and systolic blood pressure (r = 0.409, P = 0.047) in overweight and obesity cases.ConclusionThe concentrations of resistin in cases with over-weight and obesity are higher, and there is no correlation between resistin and blood glucose, blood lipids and insulin, while the serum adiponectin concentrations positively correlated with HDL-c and systolic blood pressure.