Altofrequency SNPs of mitochondrial DNA in 26 Han Chinese

ObjectiveTo explore the possible mitochondrial DNA (mtDNA) polymorphism in Han Chinese.MethodsThe complete mitochondrial genome of 26 unrelated healthy Han Chinese were extracted and sequenced.ResultsThe mtDNA nucleotide sites (2 706, 7 028, 8 860. 11 719, and 15 326) were found totally different from the Revised Cambridge Reference Sequence (rCRS). These single nucleotide polymorphisms (SNPs) were 2 706 A→G, 7 028 C→T. 8 860 A→G. 11 719 G→A, 15 326 A→G.ConclusionThese findings provide new insights into the characteristics of Han Chinese mitochondrial genetic diversity.