Clinical experimental study of Arnebia Root oil in increasing FGF expression and promoting wound surface healing

ObjectiveTo investigate the effection of Arnebia Root oil on the FGF expression in wound surface and the ability to promote wound surface healing.Methods24 wound surfaces of patients were divided into two groups. Experimental group was treated by Arnebia Root oil and the control was treated by petrolatum gauze. Histology, histochemistry, electron microscope methods and healing rate measurement were used to show the FGF expression and wound healing process.ResultsEndogenous FGF were expressed in both of the groups, in which of the experimental group was higher than that of the control group. the wound surface healing rate of experimental group was also higher and paralleled with FGF expression.ConclusionArnebia Root oil has effects to promote FGF expression and enhances wound surface repair. The wound healing mechanism between the action of Arnebia Root oil and function of FGF need further investigating.