کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3796500 1597330 2007 25 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nonalcoholic Fatty Liver Disease as a Complication of Insulin Resistance
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Nonalcoholic Fatty Liver Disease as a Complication of Insulin Resistance
چکیده انگلیسی

Nonalcoholic fatty liver disease (NAFLD) refers to a spectrum of liver damage ranging from simple steatosis to nonalcoholic steatohepatitis, advanced fibrosis, and rarely, progression to cirrhosis. The pathogenesis of NAFLD is thought to be related to insulin resistance and oxidant stress. Truncal obesity, dyslipidema, hypertension, and hyperglycemia are strongly associated with NAFLD; therefore, management of NAFLD entails identification and treatment of metabolic risk factors, improving insulin sensitivity, and increasing antioxidant defenses in the liver. This article briefly summarizes advances in our understanding of the relationship between NAFLD and the insulin resistance (metabolic) syndrome, its prevalence, natural history, and treatment.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Clinics of North America - Volume 91, Issue 6, November 2007, Pages 1125–1149
نویسندگان
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