کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3798158 1244417 2015 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Acción inmunomoduladora de las células madre mesenquimales en las enfermedades autoinmunitarias
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Acción inmunomoduladora de las células madre mesenquimales en las enfermedades autoinmunitarias
چکیده انگلیسی
Autoimmune diseases are a cluster of disorders characterized by a failure of the immune tolerance and a hyperactivation of the immune system that leads to a chronic inflammation state and the damage of several organs. The medications currently used to treat these diseases usually consist of immunosuppressive drugs that have significant systemic toxic effects and are associated with an increased risk of opportunistic infections. Recently, several studies have demonstrated that mesenchymal stem cells have immunomodulatory properties, a feature that make them candidates to be used in the treatment of autoimmune diseases. In the present study, we reviewed the role of this therapy in the treatment of systemic lupus erythematosus, Sjögren's syndrome, systemic sclerosis, Crohn's disease and multiple sclerosis, as well as the potential risks associated with its use.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medicina Clínica - Volume 144, Issue 2, 20 January 2015, Pages 88-91
نویسندگان
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