Tratamiento de los linfomas no hodgkinianos indolentes

Indolent lymphomas in localized stages (I and II) account for 20%, only 10% being in pathological stages. The possibilities for cure with radiotherapy and/or chemotherapy are approximately 50-70%. Advanced stages (IIB, III and IV) of phenotype B types account 06 for 80-90% of the cases and are candidates for systemic treatments with immunochemotherapy for those of phenotype B. Rescue treatment is one of the most important problems in this type of lymphomas, many of them needing second line treatments, with survival rates under five years, in spite of the 50% response rate. In these cases, immunochemotherapy includes more aggressive regimens, high-dose chemotherapy and combined chemoim-munoradiotherapy.