HIV/AIDS

Insomnia is common in people living with HIV and AIDS. Evidence to date suggests that there is no consistent relationship between altered sleep architecture and disease progression. The exception is late-stage HIV infection associated with cognitive impairment. The antiretroviral drug efavirenz has also been found to be a contributor but the most significant risk factor is psychological morbidity. This highlights the importance of investigation and management of underlying anxiety and depression in people presenting with persistent insomnia.