کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3848456 1598282 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Collapsing Glomerulopathy Following Anthracycline Therapy
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Collapsing Glomerulopathy Following Anthracycline Therapy
چکیده انگلیسی
We report 2 cases of anthracycline-induced collapsing glomerulopathy, one in a patient treated for peripheral T-cell lymphoma, and the other in a kidney transplant recipient treated for acute myeloid leukemia. Collapsing glomerulopathy is a distinct variant of focal segmental glomerulosclerosis (FSGS) that has been attributed to several different causes besides human immunodeficiency virus (HIV) in recent years. Previously, anthracycline use has been associated with FSGS, not otherwise specified (NOS). However, in the absence of therapy, various hematolymphoid malignancies have been associated with FSGS, NOS and collapsing glomerulopathy. In individuals who have hematolymphoid malignancy or are being treated with an anthracycline, the frequency of FSGS is extremely low. We suggest that in the following 2 patients, anthracycline use caused collapsing FSGS based on the temporal relationship, but also in the context of potentially underlying predisposing conditions. Host and environmental factors may interact to cause one morphologic form of FSGS or another.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Kidney Diseases - Volume 61, Issue 5, May 2013, Pages 778-781
نویسندگان
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