Off-Pump Coronary Artery Bypass Surgery and Acute Kidney Injury: A Meta-analysis of Randomized and Observational Studies

Analysis of the current evidence suggests a reduction in AKI using the OPCAB technique; however, studies lack consistency in defining AKI. Available RCTs are underpowered to detect a difference in AKI requiring RRT; evidence from observational studies suggests a reduction in RRT requirement. Future studies should apply a standard definition of AKI and target a high-risk population.