کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3851853 1598356 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nephrotic-Range Proteinuria in a Patient With a Giant Prolactinoma
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Nephrotic-Range Proteinuria in a Patient With a Giant Prolactinoma
چکیده انگلیسی
We report for the first time a case of nephrotic-range proteinuria adequately controlled by using dopamine agonists. A 40-year-old man was studied because of persistent asymptomatic nephrotic proteinuria despite lifestyle modifications and treatment with converting enzyme inhibitors. The renal biopsy specimen did not show histopathologic changes. In the follow-up period, a giant prolactinoma was found by chance with extremely high prolactin (PRL) values. After establishing cabergoline therapy, we achieved a remarkable decrease in both serum PRL levels and tumor mass, and surprisingly, proteinuria disappeared. We discuss the possible pathogenic mechanisms of proteinuria that may correspond to PRL level in urine (prolactinuria) or another tumor-related protein.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Kidney Diseases - Volume 51, Issue 6, June 2008, Pages 1025-1028
نویسندگان
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