Parathyroidectomy Versus Cinacalcet Hydrochloride-Based Medical Therapy in the Management of Hyperparathyroidism in ESRD: A Cost Utility Analysis

For patients with ESRD with uncontrolled hyperparathyroidism who are good candidates for either drug therapy or surgery, cinacalcet hydrochloride is the most cost-effective modality if the patient is to remain on dialysis therapy for 7.25 ± 0.25 months. Cinacalcet may be more optimal if used in patients who have high risk of mortality or who would expect to receive a kidney transplant quickly. For other subgroups, parathyroidectomy dominated.