کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3852270 | 1598389 | 2006 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Lymphoid Interstitial Lung Disease in a Patient With Acute Tubulointerstitial Nephritis and Uveitis: A New Facet of a Rare Syndrome?
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای کلیوی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Lymphoid Interstitial Lung Disease in a Patient With Acute Tubulointerstitial Nephritis and Uveitis: A New Facet of a Rare Syndrome? Lymphoid Interstitial Lung Disease in a Patient With Acute Tubulointerstitial Nephritis and Uveitis: A New Facet of a Rare Syndrome?](/preview/png/3852270.png)
چکیده انگلیسی
We report for the first time the appearance of lymphoid interstitial lung disease in a patient with tubulointerstitial nephritis and uveitis (TINU) syndrome. A 41-year-old woman with a 9-month history of recurrent bilateral iridocyclitis was referred to our division for examination of renal dysfunction. Renal biopsy showed extensive interstitial CD3+ lymphocytic infiltration; glomerular structures were unaffected. After oral corticosteroid therapy, renal function remained stable during the next few years. Uveitis was controlled by using topical steroids. Five years after first presentation, the patient developed symptoms suggestive of interstitial lung disease, combined with a relapse of uveitis. Lung biopsy showed lymphofollicular bronchiolitis (CD3+) associated with florid alveolitis. There was no evidence for acute infection or systemic disease to be the cause of this pathological state. Lung disease proved to be steroid responsive. A new pulmonary flare-up 3 years later responded to renewed treatment. Accounting for the histological findings, we assume both TINU syndrome and interstitial lung disease to be manifestations of a common autoimmune disorder.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Kidney Diseases - Volume 47, Issue 4, April 2006, Pages e55-e59
Journal: American Journal of Kidney Diseases - Volume 47, Issue 4, April 2006, Pages e55-e59
نویسندگان
Nina Hofmann, Klaus-Michael MD, Christian MD, Rüdiger MD, Martin MD, Vedat MD,