Serum Levels of Folate and Cobalamin Are Lower in Depressed Than in Nondepressed Hemodialysis Subjects

As with the general population, lower serum folate, RBC folate, and serum cobalamin levels were found in depressed as compared to nondepressed subjects on HD. Plasma levels of these vitamins may be one of many factors related to depression, but larger studies with stronger designs are needed to confirm the results of this study.