miRNA-34a Suppresses Cell Proliferation and Metastasis by Targeting CD44 in Human Renal Carcinoma Cells

Our findings indicate that miR-34a targets CD44 in renal cancer cells and suppresses renal cancer cell growth, tube formation and metastasis in vitro and in vivo. Thus, miR-34a may be a potential molecular target for novel therapeutic strategies for clear cell renal carcinoma.