کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3867499 | 1598930 | 2012 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Transforming Growth Factor-β1 Mediates Migration in Cultured Human Control and Exstrophy Bladder Smooth Muscle Cells
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کلمات کلیدی
bSMCTGF-β1SMCKClHCMCBEPBSHBSS[Ca2+]i - [Ca2 +] iACh - آهAcetylcholine - استیل کولینBladder exstrophy - اکستروفی مثانهTransforming growth factor-β1 - تبدیل فاکتور رشد β1Translational medical research - تحقیقات پزشکی ترجمهSMA - دبیرستانSmooth muscle cell - سلول عضلانی صافSmooth - صافMuscle - عضلهintracellular calcium concentration - غلظت کلسیم داخل سلولیPhosphate buffered saline - فسفات بافر شورUrinary bladder - مثانه ادرارClassic bladder exstrophy - کیست تخمدان کلاسیک
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای کلیوی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Transforming Growth Factor-β1 Mediates Migration in Cultured Human Control and Exstrophy Bladder Smooth Muscle Cells Transforming Growth Factor-β1 Mediates Migration in Cultured Human Control and Exstrophy Bladder Smooth Muscle Cells](/preview/png/3867499.png)
چکیده انگلیسی
Our results suggest that there are distinct differences in bladder smooth muscle cell function between control and exstrophy cases which persist in culture. Although resting intracellular calcium concentration was higher in control cells, proliferation rates were similar in both cell types, indicating that lower intracellular calcium concentration did not impact growth potential. In contrast, enhanced migration was observed in exstrophy cells, possibly due to excess transforming growth factor-β1 signaling, but seemingly independent of increases in intracellular calcium concentration.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Urology - Volume 188, Issue 4, Supplement, October 2012, Pages 1528-1534
Journal: The Journal of Urology - Volume 188, Issue 4, Supplement, October 2012, Pages 1528-1534
نویسندگان
Kristina D. Suson, Andrew A. Stec, John P. Gearhart, Larissa A. Shimoda,