Heterogenized hybrid catalyst of 1-sulfonic acid-3-methyl imidazolium ferric chloride over NaY zeolite for one-pot synthesis of 2-amino-4-arylpyrimidine derivatives: A viable approach

• Six different ratios of NaY zeolite supported 1-sulfonic acid-3-methyl imidazolium ferric chloride [Msim][FeCl4] are prepared as hybrid material for investigation.
• All these composites are characterized using PXRD, FT-IR, Raman, TGA, SEM, TEM, EDX, BET, ICP-OES and UV-Vis techniques.
• The gradual destruction of zeolite structure observed in FT-IR and PXRD studies via dealumination process with increasing percentage of [Msim][FeCl4] salt.
• The [Msim][FeCl4]/NaY = 0.1 composite is utilized as efficient reusable heterogeneous catalyst for one-pot synthesis of 2-amino-4-arylpyrimidines.

A new hybrid material of NaY zeolite supported 1-sulfonic acid-3-methyl imidazolium ferric chloride [Msim][FeCl4] has been developed by modifying the zeolite surface with six different w/w ratios through wet impregnation method. These composites were fully characterized by Powder XRD, FT-IR, Raman, TGA, SEM, TEM, EDX, BET, ICP-OES and Hammett acid strength measurement methods. The zeolite framework was found to be remaining preserved up to w/w ratio of 0.2 with some portion of extra framework Al species (EFAl) while crystallinity of the composites decreased from lower to higher loading. The overall thermal stability of composite materials increases up to w/w ratio of 0.1 than NaY. The catalytic performance of composite materials were examined for the novel one-pot consecutive formation of Biginelli- 3,4-dihydropyrimidin-2-(1H)-ones to 2-amino-4-arylpyrimidines. The 0.1 ratio composite material showed excellent catalytic activity up to ten consecutive cycles in solvent-free medium under the optimized reaction condition.

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