کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3884718 1249487 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Testing for causality and prognosis: etiological and prognostic models
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Testing for causality and prognosis: etiological and prognostic models
چکیده انگلیسی

Etiological research aims to investigate the causal relationship between putative risk factors (or determinants) and a given disease or other outcome. In contrast, prognostic research aims to predict the probability of a given clinical outcome and in this perspective the pathophysiology of the disease is not an issue. Multivariate modeling is a fundamental tool both to infer causality and to investigate prognostic factors in epidemiological research. The analytical approaches to etiological and prognostic studies are strictly dependent on the research question and imply knowledge of the main statistical procedures for model building and data interpretation. In this paper we describe the application of multivariate statistical modeling in etiological and prognostic research. We will mainly focus on the differences in model building and data interpretation between these two areas of epidemiologic research.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Kidney International - Volume 74, Issue 12, 2 December 2008, Pages 1512–1515
نویسندگان
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