کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3892130 1599184 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Rhabdomyolysis in a patient taking nebivolol
ترجمه فارسی عنوان
رابدومیلیز در بیمار مصرف کننده نابوولول
کلمات کلیدی
مسدود کننده های β-adrenergic؛ میوپاتی؛ نبویولول؛ رابدومیلیز
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
چکیده انگلیسی

β Blockers such as propranolol and labetalol are known to induce toxic myopathy because of their partial β2 adrenoceptor agonistic effect. Nebivolol has the highest β1 receptor affinity among β blockers, and it has never been reported to induce rhabdomyolysis until now. We report a patient who developed rhabdomyolysis after changing medication to nebivolol. A 75-year-old woman was admitted to our hospital because of generalized weakness originating 2 weeks before visiting. Approximately 1 month before her admission, her medication was changed from carvedilol 12.5 mg to nebivolol 5 mg. Over this time span, she had no other lifestyle changes causing rhabdomyolysis. Her blood chemistry and whole body bone scan indicated rhabdomyolysis. We considered newly prescribed nebivolol as a causal agent. She was prescribed carvedilol 12.5 mg, which she was previously taking, instead of nebivolol. She was treated by hydration and urine alkalization. She had fully recovered and was discharged.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Kidney Research and Clinical Practice - Volume 35, Issue 3, September 2016, Pages 182–186
نویسندگان
, , , , , , , ,