کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3892196 1250070 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Two cases of idiopathic membranous nephropathy treated with rituximab
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Two cases of idiopathic membranous nephropathy treated with rituximab
چکیده انگلیسی

Idiopathic membranous nephropathy is a common cause of nephrotic syndrome, and has been reported as a cause of idiopathic primary glomerulonephropathy in up to 90% of patients. However, the treatment options remain controversial. We report two cases of idiopathic membranous nephropathy that were treated with rituximab. A 54-year-old man and a 64-year old man were admitted for rituximab therapy. They had previously been treated with combinations of immunosuppressive agents including cyclophosphamide, cyclosporine, mycophenolate, and steroids. However, the patients' heavy proteinuria was not resolved. Both patients received rituximab therapy, 2 weeks apart. After several months of follow-up and a second round of rituximab treatment for each patient, their proteinuria decreased and partial remission of disease was achieved in both patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Kidney Research and Clinical Practice - Volume 32, Issue 3, September 2013, Pages 138–141
نویسندگان
, , , , , , , , ,