کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3896579 1250223 2013 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Endocrine and Hypertensive Disorders of Potassium Regulation: Primary Aldosteronism
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Endocrine and Hypertensive Disorders of Potassium Regulation: Primary Aldosteronism
چکیده انگلیسی

SummaryThe identification of primary aldosteronism as a common cause of resistant hypertension is a significant advance in our ability to care for patients with hypertension. Primary aldosteronism is common, and when unrecognized is associated with an increased incidence of adverse cardiovascular outcomes. Identification of primary aldosteronism is based on use of the plasma aldosterone level, plasma renin activity, and the aldosterone:renin ratio. Differentiation between unilateral and bilateral autonomous adrenal aldosterone production then guides further therapy, with use of mineralocorticoid-receptor blockers for patients with bilateral autonomous adrenal aldosterone production and laparoscopic adrenalectomy for patients with unilateral autonomous aldosterone production. In this review, we discuss in detail the pathogenesis of primary aldosteronism-induced hypertension and potassium disorders, the evaluation of the patient with suspected primary aldosteronism, and the management of primary aldosteronism, both through medications and surgery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Nephrology - Volume 33, Issue 3, May 2013, Pages 265–276
نویسندگان
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