Poly(ADP-ribose) Polymerase is Involved in the Development of Diabetic Cystopathy via Regulation of Nuclear Factor Kappa B

These results indicate that overactivated PARP and subsequent activation of NF-κB play important roles in the development of diabetic cystopathy via induction of bladder apoptosis. These findings may be applied in the development of novel therapies for patients with diabetic cystopathy.