Potential Establishment of Lung Metastatic Xenograft Model of Androgen Receptor-positive and Androgen-independent Prostate Cancer (C4-2B)

We have shown the potential establishment of a mouse lung metastatic xenograft model of androgen receptor-positive and androgen-independent C4-2B PCa tumor. However, the present model requires improvement to be a more reproducible, accurate and complete experimental model. Additional study is necessary to verify the relationship between metastasis and CTCs.