Activation of VEGF and ERK1/2 and Improvement of Urethral Function by Adipose-derived Stem Cells in a Rat Stress Urinary Incontinence Model

Peri-urethral injection of ADSCs is associated with more normal urinary function and urethral structure in rats with parturition-related incontinence. The activation of vascular endothelial growth factor and ERK1/2 may be responsible for the paracrine effects from ADSCs.