Importance of Erythrocyte Band III Anion Transporter (SLC4A1) on Oxalate Clearance of Calcium Oxalate Monohydrate Stone-formering Patients vs. Normal Controls

SLC4A1 associated changes of HCO3− and pH levels influenced the cellular oxalate levels and urinary oxalate clearance. Under normal conditions (pH 7.55) the oxalate efflux in COM was comparable with the acid stimulated oxalate efflux in NC. The addition of HCO3− compensated the flux of COM stone formers to the levels of normal controls.