Pharmacological Effect of TRK-380, a Novel Selective Human β3-Adrenoceptor Agonist, on Mammalian Detrusor Strips

TRK-380 was a potent and selective human β3-AR agonist, and the isolated human detrusor relaxation was mainly mediated by activation of the β3-AR. Consequently, TRK-380 might be a promising compound for the treatment of overactive bladder.