کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3902009 1250360 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bacterial Sepsis After Prostate Biopsy—A New Perspective
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Bacterial Sepsis After Prostate Biopsy—A New Perspective
چکیده انگلیسی

ObjectivesTo determine the incidence of sepsis following transrectal ultrasound (TRUS)-guided prostate biopsy at our center.MethodsWe retrospectively reviewed a group of 24 men who presented with urosepsis after undergoing TRUS biopsy at our center.ResultsOf the 24 men, 22 were given prophylactic ciprofloxacin. The median time to presentation of sepsis was 1 day after biopsy. The median length of hospitalization was 4 days. Escherichia coli was the most frequent cause of urosepsis (67%). Variable resistance patterns were observed. Enterobacter cloacae and Streptococcus viridans were isolated in 2 cases. No bacteria were isolated in 6 cases. Two patients who received extensive antibiotic prophylaxis still developed urosepsis. Treatment of patients infected with multiresistant anaerobic strains using metronidazole among others, proved successful. High sensitivities toward cefazolin, gentamicin, and tobramycin were observed. The number of cases reported was likely an underestimation, because some patients may have reported to other hospitals and were not captured by this study. In addition, some patients may not have developed infection and urosepsis despite harboring ciprofloxacin-resistant bacteria.ConclusionsProphylactic ciprofloxacin is still a useful option for the prevention of urosepsis after TRUS biopsy, as the incidence is relatively low. For the patient who develops urosepsis after TRUS biopsy, ciprofloxacin resistance needs to be suspected and the treatment regime should be tailored to the resistance profiles of the local region, the patient's medical history, and the culture and sensitivity reports.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Urology - Volume 74, Issue 6, December 2009, Pages 1200–1205
نویسندگان
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