A Chinese Herbal Formula, Shuganyiyang Capsule, Improves Erectile Function in Male Rats by Modulating Nos-CGMP Mediators

SGYY significantly improves the maximal intracavernous pressure in arteriogenic ED in a rat model. The underlying mechanism of action of SGYY involves increasing the expression of some main factors in the NOS-cGMP pathway and reducing the expression of PDE5.