کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3902636 1250368 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Use of Restaging Bladder Tumor Resection for Bladder Cancer Among Medicare Beneficiaries
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Use of Restaging Bladder Tumor Resection for Bladder Cancer Among Medicare Beneficiaries
چکیده انگلیسی

ObjectiveTo evaluate the use and effectiveness of restaging bladder tumor resection using population-based data. Restaging bladder tumor resection improves staging accuracy and the response to intravesical therapy. However, its use outside of a tertiary care setting, and its subsequent clinical implications, are unknown.MethodsWe identified 62 016 patients diagnosed with bladder cancer between 1992 and 2005 using SEER−Medicare data. Restaging bladder tumor resection was defined as 2 or more resections occurring within 60 days of diagnosis. Using multivariable models, we assessed the relationship between the use of restaging resection and cancer-specific survival.ResultsRestaging resection was performed in only 3064 (4.9%) of newly diagnosed bladder cancer patients, but was most common among those with high grade (7.7% vs 2.0% in low grade, P < .001) and stage (8.8% in T2 vs 2.8% in Ta/Tis, P < .001) disease. Compared to patients with muscle-invasive cancers who did not undergo restaging at diagnosis, restaging resection was associated with improved 5-year cancer-specific mortality among pathologically staged patients (20.4% vs 28.0%, P = .02), while clinically staged patients trended toward improved mortality (28.2% vs 31.9%, P = .07).ConclusionRestaging transurethral resection for bladder cancer is relatively uncommon and associated with improved survival among patients with muscle invasive bladder cancer. Greater use of restaging warrants further investigation as a simple means of improving outcomes among patients suspected of having muscle invasive disease.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Urology - Volume 78, Issue 6, December 2011, Pages 1345–1349
نویسندگان
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