کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3902639 1250368 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Defining Patient Selection for Prostate-sparing Cystectomy in Squamous Cell Carcinoma of the Urinary Bladder Associated With Bilharziasis: An Overview of 236 Patients
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Defining Patient Selection for Prostate-sparing Cystectomy in Squamous Cell Carcinoma of the Urinary Bladder Associated With Bilharziasis: An Overview of 236 Patients
چکیده انگلیسی

ObjectiveTo determine possible risk factors associated with prostate invasion in patients with squamous cell carcinoma (SCC) of the urinary bladder associated with bilharziasis.MethodsAfter obtaining approval from the medical ethics committee, we reviewed the clinical and pathologic data from 236 male patients in our department between January 2006 and October 2010 who were treated with radical cystoprostatectomy and proved to have SCC associated with bilharziasis. We reviewed the clinical and histopathologic data regarding prostate infiltration from SCC of the urinary bladder associated with bilharziasis.ResultsTwo-hundred thirty-six patients were included in this study. Prostate infiltration was present in 14 patients (5.9%). Tumor located in the bladder neck (P = .000001), tumors >5 cm (P = .009), and advanced clinical tumor stage (P = .000001) were associated with highly statistically significant increased risk of prostate invasion from SCC of the urinary bladder. Different patients' ages, high tumor grade, and regional lymph nodes' metastasis were not associated with increased risk of prostate invasion from SCC of the urinary bladder.ConclusionProstate infiltration from SCC of the urinary bladder (which is associated with bilharziasis) is not uncommon. Tumor >5 cm, bladder neck tumor, and high clinical tumor stages should be considered at least relative contraindications for prostate-sparing cystectomy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Urology - Volume 78, Issue 6, December 2011, Pages 1351–1354
نویسندگان
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