Combined “periprostatic and periapical” local anesthesia is not superior to “periprostatic” anesthesia alone in reducing pain during Tru-Cut prostate biopsy

Periprostatic lidocaine infiltration provides local anesthesia that results in improved visual analog scale pain scores. Additional apical infiltration did not improve patient discomfort further. However, comparative evidence has indicated that increasing the time elapsed between the anesthetic infiltration and the biopsy procedure may further improve pain control.