Outcome following preterm birth

Preterm birth currently occurs in approximately 12% of pregnancies and appears to be increasing despite improvements in obstetric care. Improvements in neonatal care have led to increased survival, particularly at extreme prematurity, but survival may be associated with significant morbidity. This may be acute, reflecting the difficulties in supporting an individual in a hostile extrauterine environment to which they should not be exposed, or chronic, reflecting disturbances to fragile, immature body systems. Brain, lungs, intestines and eyes are particularly vulnerable and damage may be severe. For some infants the consequences of this damage may be permanent disability and impairment. Despite this, the limited information currently available suggests that adult outcomes may be comparable with those for infants born at term.