کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3908838 | 1251196 | 2013 | 10 صفحه PDF | دانلود رایگان |
ObjectivesTo identify patterns of variation in breast cancer mortality in Europe (1980–2010), using a model-based approach.MethodsMortality data were obtained from the World Health Organization database and mixed models were used to describe the time trends in the age-standardized mortality rates (ASMR). Model-based clustering was used to identify clusters of countries with homogeneous variation in ASMR.ResultsThree patterns were identified. Patterns 1 and 2 are characterized by stable or slightly increasing trends in ASMR in the first half of the period analysed, and a clear decline is observed thereafter; in pattern 1 the median of the ASMR is higher, and the highest rates were achieved sooner. Pattern 3 is characterised by a rapid increase in mortality until 1999, declining slowly thereafter.ConclusionThis study provides a general model for the description and interpretation of the variation in breast cancer mortality in Europe, based in three main patterns.
Journal: The Breast - Volume 22, Issue 3, June 2013, Pages 244–253