کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3908994 | 1251200 | 2011 | 5 صفحه PDF | دانلود رایگان |
Survival and cause of death was investigated for Primary Surgical Therapy (PST) and Primary Endocrine Therapy (PET). Of women aged ≥75 years 113 patients received PET, 233 patients underwent PST. PST gave better survival, although this group was younger (p < 0.001). During follow-up the percentage of deaths due to breast cancer was similar and stable in both groups. Increased age was associated with a higher risk on death due to other causes (HR 1.11; CI 1.07–1.14), not on death due to breast cancer (HR 0.94; CI 0.87–1.01). The association of type of treatment and death due to breast cancer was not different between both groups in univariate analyses (HR 0.78; CI 0.44–1.39). In the multivariate model this non-significance remained after correcting for tumor size and age (HR 0.68; CI 0.33–1.42). Treatment should not be based merely on surgical treatment. PET may be an acceptable alternative.
Journal: The Breast - Volume 20, Issue 4, August 2011, Pages 365–369