کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3913677 | 1251445 | 2013 | 4 صفحه PDF | دانلود رایگان |
BackgroundThe study was conducted to assess the effectiveness of early medical abortion (EMA) in women with early pregnancy and no defined intrauterine gestational sac (IUGS) on ultrasound.Study DesignRetrospective, multicenter, observational study of oral mifepristone 200 mg and buccal misoprostol 800 mcg administered 24–48 h later for EMA (gestations ≤ 63 days). Odds ratios (ORs) [95% confidence intervals (CIs)] of EMA failure and continuing pregnancy for women with no defined IUGS vs. those with confirmed IUGS were calculated.ResultsWomen with no defined IUGS were more likely to experience EMA failure [9.0% (6/67) vs. 3.5% (465/13,345); OR (95% CI)=2.72 (1.17–6.33), p=.041] and continuing pregnancy [7.5% (5/67) vs. 0.6% (83/13,345); OR (95% CI)=12.72 (4.98–32.46), p<.001].ConclusionEMA failure is more likely in women with early pregnancy and no defined IUGS than those with gestations ≤ 63 days and confirmed IUGS.Trial RegistrationAustralian New Zealand Clinical Trials Registry identifier: ACTRN12611001051932.
Journal: Contraception - Volume 87, Issue 6, June 2013, Pages 855–858