کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3917218 | 1252103 | 2008 | 6 صفحه PDF | دانلود رایگان |
BackgroundIn the debate on the best cord clamping time in newborn infants, we hypothesized that late cord clamping enables an increased volemia due to blood transfer to the newborn from the placenta.AimTo assess whether clamping time can affect limb perfusion and heart hemodynamics in a group of 22 healthy term newborn infants.Study designA case-control study.SubjectsEleven early-clamped (at 30 s) vaginally-delivered newborn infants were compared with eleven late-clamped (at 4 min) newborns.Outcome measuresThe two groups were studied using near-infrared spectroscopy and M-mode echocardiography.ResultsLate cord clamping coincided with a higher hematocrit (median 62% versus 54%) and hemoglobin concentration (median 17.2 versus 15 g/dL), whilst there were no changes in bilirubin level. Echocardiography showed a larger end-diastolic left ventricle diameter (1.7 cm median value versus 1.5) coupled with unvaried shortening and ejection fraction values. There were no changes in calf blood flow, oxygen delivery, oxygen consumption or fractional oxygen extraction calculated from the NIRS measurements, or in foot perfusion index.ConclusionsOur results demonstrated that late cord clamping coincides with an increased placental transfusion, expressed by higher hematocrit and hemoglobin values, and larger left ventricle diameter at the end of the diastole, with no changes in peripheral perfusion or oxygen metabolism.
Journal: Early Human Development - Volume 84, Issue 3, March 2008, Pages 195–200