کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3919889 | 1599804 | 2014 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Serum AMH levels in the differential diagnosis of hyperandrogenemic conditions Serum AMH levels in the differential diagnosis of hyperandrogenemic conditions](/preview/png/3919889.png)
ObjectiveTo investigate the diagnostic potential of anti-Müllerian hormone (AMH) in the differential diagnosis of various hyperandrogenemic conditions.Study designAmong 2241 consecutive women of reproductive age who were seen at a tertiary care university hospital with complaints of acne, hirsutism, androgenetic alopecia, and menstrual dysfunction (oligomenorrhea and/or amenorrhea), 107 patients with serum 17α-hydroxyprogesterone (17α-OHP) levels higher than 2 ng/ml were recruited for this study. An ACTH stimulation test was performed, and basal serum hormonal parameters and AMH levels were measured for all patients.Results25 patients were diagnosed with late-onset congenital adrenal hyperplasia (LOCAH), and 59 patients with polycystic ovary syndrome (PCOS) had significantly higher serum AMH levels than all other groups.ConclusionAmong hyperandrogenemic patients with serum 17α-OHP levels >2 ng/ml, serum AMH levels might be introduced as a marker to be utilized clinically in the differential diagnosis of hyperandrogenemic patients, especially for identifying patients with PCOS.
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology - Volume 177, June 2014, Pages 121–125